Clinical Presentation In the first 24 hours following a toxic ingestion, symptoms are either absent or nonspecific (e.g., nausea, vomiting, malaise), and liver enzymes do not begin to rise until 2436 hours post-ingestion (6)
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However, GI AE are usually mild-to-moderate, transient, partially preventable, and rarely lead to treatment discontinuation 107
10.1182/blood-2017-09-806737 8 AngeliJ
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A specific NSAID, celecoxib, affected firstly the lower esophageal sphincter, and then, after a day, the pyloric sphincter as well